aminophylline in pediatric asthma floxin

Prospective data show that, across a range of emergency departments, 3.3% (110/3238) of pediatric asthma exacerbations required intravenous therapy (alone or in combination); magnesium sulphate was used in 60.9%, salbutamol in 55.5%, and aminophylline in 47.3% of cases . Aminophylline is used to prevent and treat wheezing, shortness of breath, and difficulty breathing caused by asthma, chronic bronchitis, emphysema, and other lung diseases. Aminophylline controls symptoms of asthma and other lung diseases but does not cure them. Methodological quality was high. : CD001276. All studies recruited children with Dip the tip of the suppository in water.

Continue to take aminophylline even if you feel well. No. Further research is unlikely to change our confidence in the estimate of effect.Magnet Designation.
Intravenous aminophylline can be used to manage exacerbations of asthma in children who do not respond to first line inhaled/nebulised therapy [].Accurate dosing is important, to ensure adequate asthma treatment, whilst reducing toxicity [2–4].Aminophylline has a widely accepted therapeutic range of 10-20mg/l, which drives dosing decisions in children [1,5]. To insert a rectal suppository, follow these steps: Remove the wrapper. In children with a severe asthma exacerbation, the addition of The Cochrane Airways Group register of trials was used to identify relevant studies. In total, 30 different intravenous treatment regimens were used, varying in drugs, dose, rate, and duration. Aminophylline has been compared with placebo or usual treatment (one study compared a control group who were managed with continuous nebulised albuterol, inhaled ipratropium and intravenous methylprednisolone with an aminophylline group given the above plus intravenous aminophylline) in children with acute asthma exacerbations in 12 RCTs involving 586 children. Ranked in all 10 specialties.Your gift today brings hope, comfort and the prospect of brighter tomorrows to children and their families.Children’s Mercy is a 501(c)3 charitable organization.

We put high value on avoiding a treatment that has not shown efficacy. © Copyright 2020 The recommendation may apply to most patients in most circumstances. Detailed Aminophylline dosage information for adults, the elderly and children. Voted one of America's best children's hospitals. Aminophylline belongs to a group of medicines known as bronchodilators. The Asthma ED team concurs that methylxanthines should not be added to the treatment of acute asthma for children presenting to the ED, even for those patients with the most severe exacerbations. We value preventing the need of mechanical ventilation via the use of parenteral beta agonists. The use of intravenous aminophylline did not result in significant additional bronchodilation compared to standard care with inhaled beta 2-agonists in patients experiencing an asthma exacerbation in the ED setting, or in a significant reduction in the risk of hospital admission. Includes dosages for Asthma - Acute; plus renal, liver and dialysis adjustments. The Asthma ED Team recommends using intramuscular epinephrine for children in impending/actual respiratory arrest based on very low quality evidence (Consensus). Intravenous aminophylline for acute severe asthma in children over two years receiving inhaled bronchodilators. Lie down on your left side and raise your right knee to your chest. Do not stop taking aminophylline without talking to your doctor. The D'Avila (2008) study did not demonstrate a decrease in hospital admission using this treatment. Treatment aims to reverse asthma by opening up the airways and targeting the underlying inflammation of the airways. Mitra AAD, Bassler D, Watts K, Lasserson TJ, Ducharme FM Mitra AAD, Bassler D, Watts K, Lasserson TJ, Ducharme FM. Take this short survey so Cochrane can better meet your needs in the future. We base this decision on clinical expertise regarding the use of epinephrine in cases of impending respiratory failure. DOI: 10.1002/14651858.CD001276.pub2We use cookies to improve your experience on our site. Recognizing excellence in nursing for the top 8 percent of hospitals nationally.U.S. Art. Intravenous aminophylline for acute severe asthma in children over two years receiving inhaled bronchodilators. Acute asthma is a common paediatric emergency prevalent in many countries.

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