These peak concentrations were attained approximately 10 hours post-dosing (range 4–24 hours).Following a once a day intravaginal dose of 100 mg of clindamycin phosphate vaginal cream 2%, administered for 7 consecutive days to 5 women with bacterial vaginosis, absorption was slower and less variable than that observed in healthy females. Although clindamycin phosphate is inactive Resistance to clindamycin is most often caused by modification of the target site on the ribosome, usually by chemical modification of RNA bases by point mutations in RNA or occasionally in proteins.
Therefore, it should be used with caution in patients receiving such agents.Long term studies in animals have not been performed with clindamycin to evaluate carcinogenic potential. Rarely, a person may develop colitis from using a vaginal clindamycin product.
Do not use on open wounds or on sunburned, windburned, dry, or irritated skin.Read and carefully follow any Instructions for Use provided with your medicine. Orally and parenterally administered clindamycin has been associated with severe colitis which may end fatally.
Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of clindamycin, even when administered by the vaginal route, because approximately 5% of the clindamycin dose is systemically absorbed from the vagina.The patient should also be advised that this cream contains mineral oil that may weaken latex or rubber products such as condoms or vaginal contraceptive diaphragms. Call your doctor for medical advice about side effects. Clindamycin topical may also be used for purposes not listed in this medication guide.You should not use clindamycin topical if you have You should not use clindamycin topical if you are allergic to clindamycin or inflammation of your intestines (also called enteritis);if you have ever had severe diarrhea caused by antibiotic medicine.It is not known whether this medicine will harm an unborn baby. Clindamycin(AntiRobe) generic is an antibiotic, prescribed for certain types of bacterial infections, including infections of the lungs, skin, blood, female reproductive organs and internal organs. Prices are for cash paying customers only and are not valid with insurance plans. Keep out of your mouth, nose, and eyes (may burn).
Approximately 5% (range 2% to 8%) of the dose was absorbed systemically. Be ready to tell or show what was 4.1 out of 5 stars 274. Events occurring in ≥1% of patients receiving clindamycin phosphate vaginal cream 2% are shown in Table 1.Other events occurring in <1% of the Clindamycin Vaginal Cream 2% groups include:In a clinical trial involving pregnant women during the second trimester, 1.7% of 180 patients who received treatment for 7 days discontinued therapy due to drug-related adverse events.
The systemic half-life was 1.5 to 2.6 hours.Clindamycin inhibits bacterial protein synthesis by binding to the 23S RNA of the 50S subunit of the ribosome. Other reported clinical experience has not identified differences in responses between the elderly and younger patients.In clinical trials involving non-pregnant women, 1.8% of 600 patients who received treatment with clindamycin phosphate vaginal cream 2% for 3 days and 2.7% of 1325 patients who received treatment for 7 days discontinued therapy due to drug-related adverse events. Version: 10.01.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Please note for the minimum order for Exports is of US$ 100. The applicator is filled when the plunger reaches its predetermined stopping point.Unscrew the applicator from the tube and replace the cap.While lying on your back, firmly grasp the applicator barrel and insert into vagina as far as possible without causing discomfort.Carefully withdraw applicator from vagina, and discard applicator.REMEMBER TO APPLY ONE APPLICATORFUL EACH NIGHT BEFORE BEDTIME, OR AS PRESCRIBED BY YOUR DOCTOR.Este envase contiene aplicadores de plástico desechables.
Tell your Clindamycin is predominantly bacteriostatic. Call your doctor for medical
Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. Clindamycin suppositories and vaginal cream may cause the same side effects as the oral or injectable forms. It is used on the skin to stop the growth of certain bacteria that cause acne.
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