Plavix side effects elderly revia

Plavix (clopidogrel)." QUESTION In the U.S., 1 in every 4 … Call your doctor for medical advice about side effects. This is not a complete list of side effects and others may occur. Clopidogrel hydrogen sulfate at recommended doses forms less of the active metabolite and so has a reduced effect on platelet activity in patients who are homozygous for nonfunctional alleles of the CYP2C19 gene, (termed “CYP2C19 poor metabolizers”). Plavix (clopidogrel bisulfate) is a thienopyridine class of drug that inhibits Tell your doctor if you have serious side effects of Plavix including:Plavix is supplied as 75 and 300 mg tablets. If you notice any other effects, check with your healthcare professional. You may report side effects to the FDA at 1-800-FDA-1088. The clinically important adverse reactions observed in trials comparing Plavix plus aspirin to placebo plus aspirin and trials comparing Plavix alone to aspirin alone are discussed below.In CURE, Plavix use with aspirin was associated with an increase in major bleeding (primarily gastrointestinal and at puncture sites) compared to placebo with aspirin (see Table 1). The incidence of intracranial hemorrhage was 0.4% for Plavix compared to 0.5% for aspirin.Other bleeding events that were reported more frequently in the Plavix group were epistaxis and hematoma.In CURE and CHARISMA, which compared Plavix plus aspirin to aspirin alone, there was no difference in the rate of adverse events (other than bleeding) between Plavix and placebo.In CAPRIE, which compared Plavix to aspirin, pruritus was more frequently reported in those taking Plavix. Cerner Multum, Inc. "UK Summary of Product Characteristics." You may report side effects to FDA at 1-800-FDA-1088.This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Headache; Joint Pain; INFREQUENT side effects… If experienced, these tend to have a Less Severe expression . No other difference in the rate of adverse events (other than bleeding) was reported.The following adverse reactions have been identified during postapproval use of Plavix. Because these reactions are reported voluntarily from a population of an unknown size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.Hemorrhages, including those with fatal outcome, have been reported in patients treated with Plavix.© Plavix Patient Information is supplied by Cerner Multum, Inc. and Plavix Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment.

These side effects may go away during treatment as your body adjusts to the medicine. These side effects may go away during treatment as your body adjusts to the medicine. Bristol-Myers Squibb, Princeton, NJ. Good & Bad Side Effects. It works in the elderly as well as in the young and in those with hepatic impairment as well as those without. You may report side effects to FDA at 1-800-FDA-1088.The following serious adverse reactions are discussed below and elsewhere in the labeling:Because clinical trials are conducted under widely varying conditions and durations of follow-up, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.Plavix has been evaluated for safety in more than 54,000 patients, including over 21,000 patients treated for one year or more. Some side effects of clopidogrel may occur that usually do not need medical attention. Tests are available to identify patients who are CYP2C19 poor metabolizers. You may report side effects to FDA at 1-800-FDA-1088. Other side effects not listed may also occur in some patients. In CURE (n=12,562), 1.3% treated with clopidogrel and aspirin compared to 1.1% placebo, as well as 0.7% of patients in CLARITY (n=3491) reported a rash. Cerner Multum, Inc. "Australian Product Information." Nearly every medical intervention has both good effects and some unwanted side effects… Plavix Side Effects by Likelihood and Severity COMMON side effects. Ask your doctor to learn more. Side effects not requiring immediate medical attention. The effectiveness of clopidogrel hydrogen sulfate results from its antiplatelet activity, which is dependent on its conversion to an active metabolite by the cytochrome P450 (CYP) system, principally CYP2C19. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Some side effects may not be reported.

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